Triple negative breast cancer: pitfalls and progress

HIGHLIGHTS

  • who: Paola Zagami from the (UNIVERSITY) have published the paper: Triple negative breast cancer: Pitfalls and progress, in the Journal: (JOURNAL) of 28/07/2022
  • how: A subanalysis of TCGA and METABRIC data found that immune-enriched TNBC were more likely to have lower somatic copy number alteration lower neoantigen burden lower clonal heterogeneity and better prognosis suggestive of effective immune surveillance and elimination38.

SUMMARY

    HISTORY OF TNBC Twenty years ago, new molecular taxonomy using gene_expression profiling illustrated that the BC represents several distinct biologic entities that are only in part . . .

     

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