Cyclosporine a modulates lsp1 protein levels in human b cells to attenuate b cell migration at low o2 levels

HIGHLIGHTS

• who: Shannon Hilchey and colleagues from the Department of Medicine, Division of Nephrology, University of Rochester Medical Center, Rochester, NY, USA have published the research: Cyclosporine A Modulates LSP1 Protein Levels in Human B Cells to Attenuate B Cell Migration at Low O2 Levels, in the Journal: (JOURNAL) of 27/07/2019
• what: Validating these modeling results the authors show experimentally that LSP1 levels in B cells increase with low O2 exposure and CyA treatment results in decreased LSP1 protein levels. The work has shown that cyclosporine A (CyA) directly alters B cell chemokine receptor . . .
  

   

  

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