HIGHLIGHTS
- who: August and collaborators from the Shenzhen University, China have published the article: Mitophagy: A potential therapeutic target for insulin resistance, in the Journal: (JOURNAL)
SUMMARY
Studies have divided the mitochondrial fission process into approximately three steps (Lee et_al, 2016; McBride and Frost, 2016). Mfn1 and Mfn2 promote the fusion of OMM, while Opa1 promotes the fusion of the inner mitochondrial membrane (IMM) (Lee et_al, 2017; Chan, 2020). Abnormal mitochondrial fission/fusion promotes increased ROS production, mitochondrial fragmentation, and energy metabolism disorders, which may lead to the development of metabolic diseases, such as . . .
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