HIGHLIGHTS
- who: . and colleagues from the University of Catania, Italy have published the article: Dose-dependent reduction of lymphocyte count and heart rate after multiple administration of LC51-0255, a novel sphingosine-1-phosphate receptor 1 modulator, in healthy subjects, in the Journal: (JOURNAL)
- what: The aim of this study was to investigate the safety, tolerability, pharmacokinetic (PK) characteristics, and pharmacodynamic (PD) characteristics of LC51-0255 after multiple ascending oral doses for 21 days in healthy Korean male subjects. Although the duration of the study was relatively short and the number of subjects was considered small . . .
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