HIGHLIGHTS
- who: Significance Statement and colleagues from the Institut de Biologie Paris Seine-Laboratoire de Biologie du Développement (IBPS-LBD), Paris, France have published the paper: The Ciliopathy Gene Ftm/Rpgrip1l Controls Mouse Forebrain Patterning via Region-Specific Modulation of Hedgehog/Gli Signaling, in the Journal: (JOURNAL) of March/27,/2019
- what: The authors show that Ftm ⫺/⫺ fetuses display severely disorganized hypothalamus and diencephalon and lack eyes. The authors have studied the role of the Ftm/Rpgrip1l ciliopathy gene in patterning of the diencephalon, hypothalamus, and eyes. Apart from the disorganization of the diencephalictelencephalic boundary . . .
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