HIGHLIGHTS
- who: BioMed Central et al. from the Address: Department of Pathology, University of Washington, Seattle, WA, USA and Department of Pathology, University of North Carolina have published the research work: Bio Med Central, in the Journal: (JOURNAL)
- how: The authors showed that activation of primary astrocytes from TR APOE mice with LPS led to TR APOE-dependent differences in cytokine secretion that were greatest in TR APOE2 and that were associated with differences in NF-κB subunit activity. The data indicated that the intracellular signaling that mediates altered gene transcription in response to LPS is . . .
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