Human rtel1 associates with poldip3 to facilitate responses to replication stress and r-loop resolution

HIGHLIGHTS

  • who: RTEL and collaborators from the Division University of , Copenhagen, Denmark have published the research work: Human RTEL1 associates with Poldip3 to facilitate responses to replication stress and R-loop resolution, in the Journal: (JOURNAL)
  • what: The authors examined the emerging role of RTEL1 in DNA replication. The authors show here that the R-loop accumulation after RTEL1 and Poldip3 depletion occurs at genomic common fragile sites, rDNA and telomeres. The authors focused on CFSs (represented by FRA3B and FRA16D) and other likely R-loop-prone loci in the genome; namely, telomeric repeats (represented by . . .

     

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