HIGHLIGHTS
- who: Tatsuaki Kurata from the Department Lund University of Clinical Microbiology, Rigshospitalet, Copenhagen, Denmark have published the paper: RelA-SpoT Homolog toxins pyrophosphorylate the CCA end of tRNA to inhibit protein synthesis, in the Journal: (JOURNAL)
- what: They transfer a pyrophosphate moiety from ATP to 30 modification inhibits both and sensing of cellular amino acid starvation by ribosome-associated Conversely the authors show some small alarmone hydrolase (SAH) enzymes can reverse of to counter growth inhibition by toxSAS. The authors propose the following model of substrate specificity change within the diversity synthetase-competent RSH enzymes . . .
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