Genomic aberrations generate fusion gene foxk2::tp63 and activate nfkb1 in cutaneous t-cell lymphoma

HIGHLIGHTS

  • who: Stefan Nagel and colleagues from the Department of Human and Animal Cell Lines, Leibniz-Institute DSMZ, Braunschweig, Germany have published the article: Genomic Aberrations Generate Fusion Gene FOXK2::TP63 and Activate NFKB1 in Cutaneous T-Cell Lymphoma, in the Journal: Biomedicines 2022, 2038 of /2022/
  • what: In the following, the authors focused on this conspicuou several other genes, includingwhich CAMK2D and UBE2D3, involved in NFkBinsignaling amplification, may activate novel oncogenic players CTCL. and the p53 pathway, respectively . The authors used CTCL cell line HH as a model as a model for this disease and . . .

     

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