The wnt receptor ryk reduces neuronal and cell survival capacity by repressing foxo activity during the early phases of mutant huntingtin pathogenicity

HIGHLIGHTS

• who: Cendrine Tourette and collaborators from the CNRS, UMR, Laboratory of Neuronal Cell Biology and Pathology, Paris, France, Sorbonnes Universités, University Pierre and Curie (UPMC) Univ Paris , have published the article: The Wnt Receptor Ryk Reduces Neuronal and Cell Survival Capacity by Repressing FOXO Activity During the Early Phases of Mutant Huntingtin Pathogenicity, in the Journal: (JOURNAL) of June/24,/2014
• what: The authors show that the Wnt receptor Ryk a protein known to be important for neurogenesis is increased in different animal models of HD before or during the early phases of the . . .
  

   

  

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