Mechanical control of cell migration by the metastasis suppressor tetraspanin cd82/kai1

HIGHLIGHTS

  • who: Laura Ordas et al. from the Centre de Biologie Structurale (CBS), CNRS, INSERM, University, France have published the research work: Mechanical Control of Cell Migration by the Metastasis Suppressor Tetraspanin CD82/KAI1, in the Journal: Cells 2021, 10, 1545. of 15/06/2021
  • what: The authors propose that it regulates single-epithelial 2D cell migration through tuning of membrane tension which can induce caveolae disassembly and caveolin1 release.
  • how: Single cells in the Supplementary Movies 1 and 2 were then tracked using MTrackJ (ImageJ) and migration data were analyzed using the DiPer . . .

     

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