The tutase urt1 connects decapping activators and prevents the accumulation of excessively deadenylated mrnas to avoid sirna biogenesis

HIGHLIGHTS

  • who: Hélène Scheer from the CNRS University of have published the article: The TUTase URT1 connects decapping activators and prevents the accumulation of excessively deadenylated mRNAs to avoid siRNA biogenesis, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
  • what: The authors show that the Arabidopsis TUTase URT1 is integrated in an interaction network comprising the deadenylation complex CCR4-NOT and other translation repressors/decapping activators, including DCP5, the plant ortholog of the translational inhibitor/decapping activator Scd6 or LSM14A. The GFP mRNA uridylation pattern resembles the ones typically observed for Arabidopsis mRNAs10-12 and . . .

     

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