Loss of function of ywhah in mice induces deafness and cochlear outer hair cells’ degeneration

HIGHLIGHTS

  • who: L Buret from the (UNIVERSITY) have published the research: Loss of function of Ywhah in mice induces deafness and cochlear outer hair cells' degeneration, in the Journal: (JOURNAL)
  • what: The authors have investigated the function of 14-3-3eta in both auditory and visual systems, and the authors report that the loss of 14-3-3eta protein is associated with cochlear hair cells' degeneration. This study shows the essential role of 14-3-3eta in OHC survival. The authors report for the first time YWHAH variants that can significantly alter the antiapoptotic function of . . .

     

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