Common variants in alzheimer’s disease and risk stratification by polygenic risk scores

HIGHLIGHTS

  • who: Itziar Rojas from the (UNIVERSITY) have published the paper: Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of 17/07/2020
  • what: The authors aim to comprehend and expand the knowledge of the genetic landscape underlying AD and provide additional evidence that a PRS of variants can be a robust tool to select high risk individuals with an earlier AAO. Next, the authors aimed at replicating the associated loci in 16 cohorts (19,087 AD cases and 39,101 controls in total . . .

     

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