HIGHLIGHTS
- who: GPCR et al. from the University Wollongong, Australia have published the paper: LEAP2 Impairs the Capability of the Growth Hormone Secretagogue Receptor to Regulate the Dopamine 2 Receptor Signaling, in the Journal: (JOURNAL)
- what: Based on the data , the authors propose that regulation of CaV2.2 currents contributes to this effects of LEAP2. The authors show that LEAP2 impaired the capability of GHSR to inhibit the basal and dopamine-evoked D2R-mediated reduction of CaV2.2 currents, which also depends on ghrelin-independent Gq signaling coupled to GHSR. The authors show here that LEAP2 . . .
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