Multifunctional protein 4.1r regulates the asymmetric segregation of numb during terminal erythroid maturation

HIGHLIGHTS

  • who: Shu-Ching Huang from the (UNIVERSITY) have published the Article: Multifunctional protein 4.1R regulates the asymmetric segregation of Numb during terminal erythroid maturation, in the Journal: (JOURNAL) of July/28,/2021
  • what: The authors show that the actin-binding protein 4.1R stabilizes astral microtubules and recruits LGN-NuMA to the cell cortex, thereby promoting interactions between the mitotic spindle and the cell periphery for spindle orientation.

SUMMARY

    During symmetric cell division, a stem_cell divides into two stem_cells (symmetric renewal) that allow the expansion of progenitors or into two . . .

     

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