Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer

HIGHLIGHTS

  • who: Krystal English from the Division Internal Medicine, Department Symptom Research, The University Texas MD Anderson Cancer Center, Houston, TX, USA have published the Article: Astrocytes rescue neuronal health after cisplatin treatment through mitochondrial transfer, in the Journal: (JOURNAL)
  • what: The authors show that siRNA-mediated knockdown the RhoGTPase Miro-1 in reduced mitochondrial transfer from to and prevented the normalization neuronal calcium dynamics. The authors propose that transfer functional from to is an important repair mechanism to protect the vulnerable against the toxic effects The aim of this study is to test the hypothesis . . .

     

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