Cxcr7/ackr3-targeting ligands interfere with x7 hiv-1 and hiv-2 entry and replication in human host cells

HIGHLIGHTS

  • who: Thomas D'huys from the Laboratory of Virology and Chemotherapy, Department of Microbiology and Immunology, Rega Institute for have published the Article: CXCR7/ACKR3-targeting ligands interfere with X7 HIV-1 and HIV-2 entry and replication in human host cells, in the Journal: (JOURNAL)
  • what: Using this model CXCR7-mediated viral was demonstrated for several clinical isolates well laboratory strains. The latter chemokine receptor CXCR7, also called Atypical Chemokine Receptor 3 (ACKR3), is the focus of this study. The authors evaluated the role of CXCR7 as an alternative HIV coreceptor and investigated to . . .

     

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