Dealing with difficult clients via personalized chaperone inhibitors

HIGHLIGHTS

  • who: Andrew W. Truman from the DepartmentThe University of North Carolina at Charlotte, Charlotte, North Carolina, USA have published the paper: Dealing with difficult clients via personalized chaperone inhibitors, in the Journal: (JOURNAL)
  • future: Future directions may include understanding the 2 J. Biol.

SUMMARY

    Published EDITORS' PICK HIGHLIGHT: Disrupting DNAJA1-p53 in cancer counterpart Ydj1 bind, stabilize, and regulate the activity of the ribonucleotide reductase (RNR) complex in both yeast and mammalian cells. Inhibition of DNAJA1 function through either knockout via CRISPR-CAS9 or via the novel small_molecule 116-9e developed . . .

     

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