Ex vivo oncolytic virotherapy with myxoma virus arms multiple allogeneic bone marrow transplant leukocytes to enhance graft versus tumor

HIGHLIGHTS

  • who: Cameron L. Lilly from the University of Florida, Gainesville, FL, USA have published the research: Ex Vivo Oncolytic Virotherapy with Myxoma Virus Arms Multiple Allogeneic Bone Marrow Transplant Leukocytes to Enhance Graft versus Tumor, in the Journal: (JOURNAL)
  • what: Unexpectedly the authors show that both neutrophils and activated T cells from the donor function as virus-armed carrier cells and MYXV-preloaded cells enhanced MM killing. The authors report that, in stark contrast to all human MM tested, this murine MOPC315.BM cell line is resistant to direct infection with MYXV because of a . . .

     

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