HIGHLIGHTS
- who: Edward S. Parsons from the University College London, London WC H AH, UK have published the article: Single-molecule kinetics of pore assembly by the membrane attack complex, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS
- what: From the analysis of the binding kinetics, and the C5b-7 dose-dependent C8 and C9 binding response, the authors show that the stoichiometry of the complex is determined by C5b-7 binding (Supplementary Fig 8a). In doing so, the authors determine a characteristic initiation time τinit=912 ± 32 s (Fig 3b). The authors show that once activated . . .
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