Potential metabolic resistance mechanisms to ivermectin in anopheles gambiae: a synergist bioassay study

HIGHLIGHTS

  • who: Patricia Nicolas from the (UNIVERSITY) have published the Article: Potential metabolic resistance mechanisms to ivermectin in Anopheles gambiae: a synergist bioassay study, in the Journal: (JOURNAL)
  • what: Although this approach has garnered attention development of is a potential pitfall. The authors evaluate the potential role of xenobiotic pumps and cytochrome enzymes in protecting mosquitoes against by active efflux and metabolic detoxification respectively. The authors assessed the interaction of different chemical inhibitors and inducers of CYP and P-gp with ivermectin in An. gambiae s.s. The authors investigated whether and how CYPs and P . . .

     

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