Human mll/kmt2a gene exhibits a second breakpoint cluster region for recurrent mll⠍usp2 fusions

HIGHLIGHTS

• who: Claus Meyer from the Department of Haematology, Division of Cancer and Genetics, School of Medicine, Cardiff University, Cardiff, UK have published the article: Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL⠍USP2 fusions, in the Journal: (JOURNAL) of 15/03/2019
• what: The authors show that modulation of Sts-1 expression by dexamethasone influences TKI sensitivity of Ph+ ALL cells.
• how: To assess the role of Sts-1 in Bcr-Abl-driven leukemogenesis the authors examined the induction of Bcr-Abl p210- induced CML-like disease in . . .
  

   

  

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