Zfp57 inactivation illustrates the role of icr methylation in imprinted gene expression during neural differentiation of mouse escs

HIGHLIGHTS

• who: Basilia Acurzio from the DepartmentUniversity of have published the research work: Zfp57 inactivation illustrates the role of ICR methylation in imprinted gene expression during neural differentiation of mouse ESCs, in the Journal: Scientific Reports Scientific Reports of 12/02/2021
• how: For this study the authors used ESCs that were hybrid between the genetically divergent M. m. molossinus strain JF1 and C57BL6/J so that at almost all imprinted genes the parental alleles could be told apart. An unexpected finding of this study was that although the Zfp57-/- cells were able to leave the . . .
  

   

  

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