HIGHLIGHTS
- who: Haruka Munezane from the Graduate School The University of Tokyo, Tokyo, Japan have published the research: Roles of Collagen XXV and Its Putative Receptors PTPσ/δ in Intramuscular Motor Innervation and Congenital Cranial Dysinnervation Disorder, in the Journal: (JOURNAL) of December/24,/2019
- what: The authors report that muscle-derived collagen XXV is indispensable for intramuscular innervation. developing skeletal muscles Col25a1 expression is tightly regulated by muscle excitation. vitro and cell-based assays reveal a direct interaction between collagen XXV and receptor protein tyrosine phosphatases (PTPs) s and d. The authors demonstrate that muscle-derived . . .
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