HIGHLIGHTS
- who: Akihito Hishikawa from the Department Keio University , Shinanomachi, Shinjuku-ku, Tokyo, Japan have published the research: Decreased KAT5 Expression Impairs DNA Repair and Induces Altered DNA Methylation in Kidney Podocytes, in the Journal: (JOURNAL) of January/29,/2019
- what: The authors report that KAT5-mediated damage is essential for the maintenance of kidney and is associated with Podocyte-specific KAT5-knockout mice develop severe albuminuria with increased double-strand breaks (DSBs) increased of the nephrin promoter region and decreased nephrin expression. The authors focused on podocyte KAT5, which has also been reported to be . . .
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