Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in uk biobank and generation scotland

HIGHLIGHTS

  • who: Aleix Arnau-Soler from the (UNIVERSITY) have published the paper: Genome-wide by environment interaction studies of depressive symptoms and psychosocial stress in UK Biobank and Generation Scotland, in the Journal: (JOURNAL)
  • what: This approach provides greater power to detect susceptibility variants in traits with low prevalence71.
  • how: The predictive improvement of combining PRSGxE and PRSMDD/PRSD effects over PRSMDD/PRSD effects alone was tested for significance using the likelihood ratio test (LRT).
  • future: Although the results suggest that both depressive symptom measures are correlated with lifetime depression status different . . .

     

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