HIGHLIGHTS
- who: Retrovirology and colleagues from the , BP60, EVRY , France have published the article: Bio Med Central, in the Journal: (JOURNAL)
- what: The authors show infectivity of HIV-1 mutants bearing S149A and S178A in can be efficiently restored when pseudotyped with vesicular stomatitis virus envelope glycoprotein addresses the mutant cores through the endocytic pathway rather than by fusion at the plasma membrane. Analyzing key steps of the viral life cycle, the authors demonstrate that all three residues are crucial for the formation of properly assembled HIV-1 cores and deal with distinct functions, including Gag . . .
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