Ralb gtpase: a critical regulator of dr5 expression and trail sensitivity in kras mutant colorectal cancer

HIGHLIGHTS

• who: Hajrah Khawaja from the were obtained from DrMontagut (Barcelona, Spain) and Prof. Bardelli, respectively17, . , Caspase, wildtype (WT) and null paired cells, parental and knockout cells, and p, parental and matched isogenic p, null CRC cells were a gift from Prof. G. Lahav (Harvard Medical School, Boston)19, Prof. M. Rehm (University of Stuttgart) and Prof. B. Vogelstein (Johns Hopkins University, Baltimore), respectively, and were grown in McCoy's , A Modified Medium. All cells were passaged for a maximum of two months. Cell lines were tested for mycoplasma contamination every month using the MycoAlert™ Mycoplasma Detection Kit . . .
  

   

  

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