Development of fe3o4 core-tio2 shell nanocomposites and nanoconjugates as a foundation for neuroblastoma radiosensitization

HIGHLIGHTS

  • who: William Liu from the Department of Radiation, USA have published the research work: Development of Fe3O4 core-TiO2 shell nanocomposites and nanoconjugates as a foundation for neuroblastoma radiosensitization, in the Journal: (JOURNAL)
  • what: The authors evaluated bare metaiodobenzylguanidine (MIBG) and Results: The authors confirmed previous assessment that MIBG may accumulate in mitochondria (Gaze et_al 1991) as well as cytosol (Additional file 1: Figures S3 and S4).
  • future: Studies are necessary to evaluate mechanistic basis for this increased radiosensitization effect. Much additional work will be necessary to evaluate possible benefits of targeted nanoconjugates . . .

     

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