Emerging southeast asian pfcrt mutations confer plasmodium falciparum resistance to the first-line antimalarial piperaquine

HIGHLIGHTS

• who: Leila S. Ross from the Columbia University New York, NY, USA have published the research: Emerging Southeast Asian PfCRT mutations confer Plasmodium falciparum resistance to the first-line antimalarial piperaquine, in the Journal: NATURE COMMUNICATIONS NATURE COMMUNICATIONS of March/15,/2016
• what: The authors report compelling evidence that emerging mutations in PfCRT can mediate high-level resistance to PPQ (Figs 2 and 3).
• how: To further investigate pfcrt allelic diversity in Cambodia the authors analyzed the P. falciparum genome sequences from an additional 93 patient isolates collected by researchers at the Pasteur . . .
  

   

  

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