Fucoidan prevent murine autoimmune diabetes via suppression tlr4-signaling pathways, regulation dc/treg induced immune tolerance and improving gut microecology

HIGHLIGHTS

• who: Meilan Xue from the The experiments were carried out according to the National Institutes of Health Guide for Care and Use of Laboratory Animals (Publication No85-23, revised, ). Animal care and the protocols were in accordance with the Animal Experiment Guidelines of Qingdao University of Medicine and ethical approval was obtained from Qingdao University of Medicine. Male NOD mice at , weeks-old were obtained from Beijing Vital River Laboratory Animal Technology Co [, ]. Ltd. (Beijing, China). The mice were housed in a controlled environment at a set temperature (22, °C) and humidity (, %) and under a, h light . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.