Selective modulation of subtype iii ip3r by akt regulates er ca2+ release and apoptosis

HIGHLIGHTS

• who: S Marchi from the DepartmentUniversity of Ferrara, Ferrara, Italy have published the paper: Selective modulation of subtype III IP3R by Akt regulates ER Ca2+ release and apoptosis, in the Journal: (JOURNAL)
• what: The work demonstrates that Akt preferentially exerts its anti-apoptotic role through inhibition of Ca2 - release by IP3R type III .
• how: This result is in perfect agreement with the weak Akt activity at the reticular level 45 kDa Actin 4 10 s. The authors have used different cell lines expressing different subtypes of IP3R ratio to understand if Akt . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or Email

  Password

  Remember me

  Lost your password?

  If you don't have an account, you can create one here.