Inactivation of pi3-k/akt and reduction of sp1 and p65 expression increase the effect of solamargine on suppressing ep4 expression in human lung cancer cells

HIGHLIGHTS

  • who: YuQing Chen from the Laboratory of Tumor Biology, Department of Medical Oncology, Guangdong University of Guangzhou Traditional Chinese Medicine, Guangzhou, Guangdong Province, China have published the research work: Inactivation of PI3-K/Akt and reduction of SP1 and p65 expression increase the effect of solamargine on suppressing EP4 expression in human lung cancer cells, in the Journal: (JOURNAL)
  • what: The authors explored the potential mechanism by which solamargine inhibits growth of human lung cancer cells.
  • how: The primers used in this study were designed as follows EP4 forward 5'- TCGCGCAAGGAGCAGAAGGACAC -3' reverse . . .

     

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