HIGHLIGHTS
- who: Frédéric Antonio Carvalho and colleagues from the (UNIVERSITY) have published the research work: Crohn's disease-associated Escherichia coli LF82 aggravates colitis in injured mouse colon via signaling by flagellin, in the Journal: (JOURNAL) of January/14,/2008
- what: The authors used the dextran sulfate sodium (DSS)-injured mouse colon model to investigate the ability of pathogenic AIEC LF82 bacteria compared to that of nonpathogenic LF82 mutants to aggravate colitis and show that flagella are the major virulence factor involved in the potentiation of inflammatory mucosal immune_response.
- how: Animal care . . .
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