At embryo implantation site il-35 secreted by trophoblast, polarizing t cells towards il-35+ il-10+ il-4+ th2-type cells, could favour fetal allograft tolerance and pregnancy success

HIGHLIGHTS

• who: Letizia Lombardelli et al. from the Department of Experimental and Clinical Medicine, University of Florence, Florence, Italy have published the paper: At Embryo Implantation Site IL-35 Secreted by Trophoblast, Polarizing T Cells towards IL-35+ IL-10+ IL-4+ Th2-Type Cells, Could Favour Fetal Allograft Tolerance and Pregnancy Success, in the Journal: (JOURNAL)
• what: The authors report here the first evidence of the IL-35+, IL-10+, IL-4+ Th2-type CD4+ T-cells that are polarized in response to very low levels of IL-35 that are compatible with those secreted . . .
  

   

  

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