Elf5 is a potential respiratory epithelial cell-specific risk gene for severe covid-19

HIGHLIGHTS

  • who: Maik Pietzner from the (UNIVERSITY) have published the Article: ELF5 is a potential respiratory epithelial cell-specific risk gene for severe COVID-19, in the Journal: (JOURNAL) of 10/01/2022
  • what: The authors show that ELF5 is specifically expressed in epithelial_cells of the respiratory system, such as secretory and alveolar type 2 cells, using single-cell_RNA_sequencing and immunohistochemistry. The authors demonstrate the ability of genetically informed plasma proteomics to identify causal genes and proteins for severe COVID-19 and pinpoint the responsible cell types through the integration of orthogonal data. The authors provide . . .

     

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