Mesotheliomas in genetically engineered mice unravel mechanism of mesothelial carcinogenesis

HIGHLIGHTS

  • who: Didier Jean and Marie-Claude Jaurand from the Université Paris Descartes, Labex Immuno-Oncologie, Sorbonne Paris Cité, Paris, France have published the Article: Mesotheliomas in Genetically Engineered Mice Unravel Mechanism of Mesothelial Carcinogenesis, in the Journal: (JOURNAL)
  • what: The aim of the manuscript was to compare mesothelioma models to human malignant mesothelioma and to specify the clue genes playing a role in mesothelial carcinogenesis. Many of this studies focus on target therapy to counteract the physio-pathological mechanisms allowing mesothelioma cells to grow in and invade their microenvironment, and to escape from the immune . . .

     

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