Roles of polymorphonuclear neutrophils in ischemic brain injury and post-ischemic brain remodeling

HIGHLIGHTS

  • who: Ayan Mohamud Yusuf et al. from the Department of Neurology, University Hospital, Germany, Center for Translational and Behavioral have published the article: Roles of Polymorphonuclear Neutrophils in Ischemic Brain Injury and Post-Ischemic Brain Remodeling, in the Journal: (JOURNAL) of 30/Nov/2021
  • what: In this study, NETs were identified based on citrullinated histone H3 (H3Cit) abundance, enrichment of Sytox green-labeled DNA fibers and the presence of the PMN marker Ly6G .
  • future: Future studies will MMP9 VEGF Arginase CCL2 CCL5 Depending on the microenvironment neutrophils adapt an N1 or N2 phenotype . . .

     

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