HIGHLIGHTS
- who: Piero Lo Monaco et al. from the (UNIVERSITY) have published the paper: 2'-O-Methylation of Ribosomal RNA: Towards an Epitranscriptomic Control of Translation?, in the Journal: (JOURNAL)
- how: Similar observations were made for 20 -O-Me and ψ individually and led to the conclusion that the lack of chemical modifications in at least two to three positions was necessary to observe an impact on cell growth and on the protein synthesis capacity of yeast cells. Of note a similar observation was made with ribosomes carrying an altered ψ content further strengthening the 8 of 13 . . .
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