HIGHLIGHTS
- who: Jonas Friard from the (UNIVERSITY) have published the article: LRRC8/VRAC channels exhibit a noncanonical permeability to glutathione, which modulates epithelial-to-mesenchymal transition (EMT), in the Journal: (JOURNAL)
- what: The authors explored the intriguing ability of LRRC8/VRAC to transport glutathione (GSH) the major cellular reactive oxygen species (ROS) scavenger and its involvement in epithelial-to-mesenchymal transition (EMT) a cellular process in which cellular oxidative status is a crucial step. The authors first evaluated the ability of LRRC8/ VRAC to transport GSH under hypotonic conditions and then assessed the role of LRRC8 . . .
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