Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (nafl/nash)

HIGHLIGHTS

  • who: Xiaohan Xu from the (UNIVERSITY) have published the article: Targeted therapeutics and novel signaling pathways in non-alcohol-associated fatty liver/steatohepatitis (NAFL/NASH), in the Journal: Gut microbiota of 12/04/2022
  • what: The authors focus on the signaling pathways that drive NAFL/NASH pathogenesis and summarize the relevant agents and therapies. Multiple types of cell death, including apoptosis, necroptosis, pyroptosis, and ferroptosis, as well as autophagy, are associated with the development of NAFL/ NASH.72,293,294 Among targeting different formats of cell death, inhibition of apoptosis has achieved promising results, here . . .

     

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