HIGHLIGHTS
- who: Francesco Morra from the Institute for the Experimental Endocrinology and Oncology, Research National Council, CNR, Naples, Italy Department of Medicine and Surgery, University of Milano-Bicocca have published the article: The disruption of the CCDC6 - PP4 axis induces a BRCAness like phenotype and sensitivity to PARP inhibitors in high-grade serous ovarian carcinoma, in the Journal: (JOURNAL)
- what: The authors reported that in ovarian cells a physical or functional loss of CCDC6 results synthetic lethal with the by affecting the HR repair. The PARP inhibitors' extraordinary activity in cellular systems lacking HR repair has . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.