HIGHLIGHTS
- who: Marie Breton from the 1405, CNRS Institut Gustave Roussy, Villejuif, France have published the Article: Lipothioureas as Lipids for Gene Transfection: A Review, in the Journal: Pharmaceuticals 2011, 4, 1381-1399 of 11/Oct/2011
- what: For the purpose of this review, the authors will focus on neutral lipothioureas, for which interactions with negatively charged serum proteins and proteoglycans are expected to be greatly reduced.
- how: The lysine derivative 6 was tested in presence of DPPC as formulated for in_vitro studies.
- future: In_vivo evaluations on relevant models should be performed . . .
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