Il-1 and il-23 mediate early il-17a production in pulmonary inflammation leading to late fibrosis

HIGHLIGHTS

• who: Paméla Gasse and colleagues from the University of Orleans and CNRS, UMR6218, Orleans, France, University of V and CNRS, UMR8147, France, INSERM, Université Rennes, Rennes have published the research work: IL-1 and IL-23 Mediate Early IL-17A Production in Pulmonary Inflammation Leading to Late Fibrosis, in the Journal: (JOURNAL) of August/16,/2011
• what: The authors show that bleomycin or IL-1b-induced lung injury leads to increased expression of early IL-23p19 and IL-17A or IL-17F expression. Using FACS analysis the authors show a very early IL-17A . . .
  

   

  

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