The kinase chemogenomic set (kcgs): an open science resource for kinase vulnerability identification

HIGHLIGHTS

  • who: Carrow I. Wells and colleagues from the Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA have published the Article: The Kinase Chemogenomic Set (KCGS): An Open Science Resource for Kinase Vulnerability Identification, in the Journal: (JOURNAL)
  • what: This research has generated its first manuscript from a screen which revealed a striking synthetic lethality between Chk1 inhibition and cyclin F loss .
  • how: Encouraged by these results the authors proposed a community experiment to build an optimized kinase chemogenomic set (KCGS) to cover every human kinase . The . . .

     

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