Synthetic secoisolariciresinol diglucoside attenuates established pain, oxidative stress and neuroinflammation in a rodent model of painful radiculopathy

HIGHLIGHTS

  • who: Sonia Kartha and colleagues from the Department of Bioengineering, University of Pennsylvania, Philadelphia, PA, USA have published the Article: Synthetic Secoisolariciresinol Diglucoside Attenuates Established Pain, Oxidative Stress and Neuroinflammation in a Rodent Model of Painful Radiculopathy, in the Journal: Antioxidants 2020, 9, 1209 of /2020/
  • what: This study investigated if repeated systemic administration of synthetic SDG after a root compression reduces the established pain oxidative stress and spinal glial activation that are typically evident. 3 of 16 Since SDG is capable of both detoxifying harmful oxidative stress species as well as inducing the endogenous . . .

     

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