Human mitochondrial trna processing (∗)

HIGHLIGHTS

• who: Walter Rossmanith from the (UNIVERSITY) have published the paper: Human Mitochondrial tRNA Processing (∗), in the Journal: (JOURNAL)
• what: The authors report the precise 5' - and 3' -endonucleolytic processing of human mitochondrial tRNA precursors in HeLa cell mitochondrial extracts and the 3' -terminal CCA addition to these processed mitochondrial tRNAs. The authors demonstrate that human cells contain two distinct activities that remove 5' leaders from pre-tRNAs (RNase pes)).
• how: Processing of Mitochondrial tRNA Precursors in Vitro-To identify the enzymatic activities for human mitochondrial pre-tRNA processing the authors employed human mitochondrial . . .
  

   

  

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