The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments

HIGHLIGHTS

• who: Heike Rampelt from the (UNIVERSITY) have published the paper: The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments, in the Journal: (JOURNAL)
• what: We conclude that the mitochondrial carrier pathway possesses a much higher flexibility than anticipated and can transport transmembrane helices in a paired or nonpaired fashion and direct the precursor N-termini into the intermembrane space (canonical carriers, Tim17/22/ 23) or matrix (MPC proteins).

SUMMARY

The inner mitochondrial membrane harbors a multitude of carrier proteins that belong to the mitochondrial carrier . . .

 



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