Human monoclonal antibody combination against sars coronavirus: synergy and coverage of escape mutants

HIGHLIGHTS

  • who: Hans Wilhelm Doerr and colleagues from the Crucell Holland BV, Leiden, Netherlands, Department of Microbiology, The University of Hong Kong, Queen Mary Hospital, Hong Kong Special Administrative Region of have published the paper: Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants, in the Journal: (JOURNAL)
  • what: Because enhancement of SARS-CoV infection by subneutralizing antibody concentrations is of concern the authors show here that anti-SARS-CoV antibodies do not convert the abortive infection of primary human macrophages by SARS-CoV into a productive one. The authors propose that . . .

     

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